- Asynchronous Circuits and Systems Group
- Columbia Automated Vision Environment
- Columbia Computer Graphics Group
- Computational Biology Bi-Group
- Columbia Architecture and Design Lab
- Computer Architecture and Security Technologies Lab
- Computer Graphics & User Interfaces Lab
- Computer Vision and Graphics Center
- Database Research Group
- Digital Video and Multimedia Lab
- Distributed Computing and Communications Laboratory
- Distributed Network Analysis Research Group
- Information-Based Complexity
- Internet Real-Time Laboratory
- Intrusion Detection Systems
- Languages and Compilers Group
- Machine Learning Lab
- Natural Language Processing Group
- Network Security Laboratory
- Programming Systems Laboratory
- Robotics Laboratory
- Software Systems Laboratory
- Spoken Language Processing Group
- System-Level Design Group
- Systems Security Center
- Theory of Computing Group
