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 <title>Itsik Pe&#039;er</title>
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 <title>Mapping causal variants underlying common diseases in founder populations</title>
 <link>http://ron.cs.columbia.edu/drupal/node/77</link>
 <description>&lt;p&gt;Elucidating common variants underlying complex human diseases is&lt;br /&gt;
an important first step for implicating novel biological pathways, and&lt;br /&gt;
holds the potential for future therapies.&lt;/p&gt;
&lt;p&gt;We have developed methods to map common and rare genetic&lt;br /&gt;
variation to evolutionarily and biomedically relevant traits in large-&lt;br /&gt;
scale populations: in particular, genome-wide association mapping&lt;br /&gt;
(GWAS) in founder populations such as South Pacific Islanders and&lt;br /&gt;
Ashkenazi Jews. In populations with reduced genetic, phenotypic and&lt;br /&gt;
environmental heterogeneity, the connection between the genotype&lt;/p&gt;
&lt;p&gt;&lt;a href=&quot;http://ron.cs.columbia.edu/drupal/node/77&quot; target=&quot;_blank&quot;&gt;read more&lt;/a&gt;&lt;/p&gt;</description>
 <comments>http://ron.cs.columbia.edu/drupal/node/77#comments</comments>
 <pubDate>Wed, 12 Oct 2011 02:44:40 +0000</pubDate>
 <dc:creator>mg2880</dc:creator>
 <guid isPermaLink="false">77 at http://ron.cs.columbia.edu/drupal</guid>
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