Itsik Pe'er - Teaching |
This course is intended to introduce students of both computational and bio-medical skill sets to current quantitative understanding of mammalian genomics and prepare them to computational research in the field. The course is interdisciplinary in nature, aiming at a broad scope of Topics include: Sequencing of the human genome, vertebrate genomes, highlighting parts of the genome, sequence conservation, sequence variation, structural mutations, primate evolution. The computational toolbox discussed includes parameter inference, likelihood analysis, hidden Markov and other graphical models, approximate string matching and other algorithms. [Spring '07]
This course is intended to introduce students of both computational and bio-medical skill sets to current quantitative understanding of human genetics and prepare them to computational research in the field. Topics include: genetics of a single site, coalescence with recombination, history of humans, mapping rare mutations through linkage, mapping common variants through association, isolated and admixed populations, natural selection, copy number changes, model organisms, and genotyping technologies. The computational toolbox discussed includes parameter inference, likelihood analysis, hidden Markov and other graphical models, eigenvalue decompositions, and classification problems. [Fall'07] [Fall'06]
I offer several research-oriented projects, each with potential to be pursued to different depths, to fit different levels of credit requirements.
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